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Index > Protein center > Gpx4(Gene name) > Rat
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  • Gpx4 (Gene name),
  • Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (Protein name ),  GPX41_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Gpx4;
    Protein name:
    Phospholipid hydroperoxide glutathione peroxidase, mitochondrial(PHGPx);
    Alternative:
    Glutathione peroxidase 4(GPx-4;GSHPx-4);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
    Subcellular Location:
    Mitochondrion Cytoplasm
    Protein Attributes:
    Sequence length:
    197
    Sequence:
    50:
    MSWGRLSRLL | KPALLCGALA | VPGLAGTMCA | SRDDWRCARS | MHEFAAKDID | 
    100:
    GHMVCLDKYR | GCVCIVTNVA | SQUGKTDVNY | TQLVDLHARY | AECGLRILAF | 
    150:
    PCNQFGRQEP | GSNQEIKEFA | AGYNVRFDMY | SKICVNGDDA | HPLWKWMKVQ | 
    197:
    PKGRGMLGNA | IKWNFTKFLI | DKNGCVVKRY | GPMEEPQVIE | KDLPCYL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat PHGPx
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    E9951m
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    ELISA Kit for Rat PHGPx
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    E9951h
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    ELISA Kit for Rat PHGPx
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    E9951b
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    ELISA Kit for Rat PHGPx
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    ELISA Kit for Rat PHGPx
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    E9951r
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    ELISA Kit for Rat PHGPx
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    ELISA Kit for Rat PHGPx
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    E9951r
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    CLIA Kit for Rat PHGPx
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    U9951m
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    CLIA Kit for Rat PHGPx
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    96T
    CLIA Kit for Rat PHGPx
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    U9951r
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    CLIA Kit for Rat PHGPx
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    U9951h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat PHGPx
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    U9951m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat PHGPx
    Cat.:
    U9951b
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    MSDS:
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    96T
    CLIA Kit for Rat PHGPx
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    U9951p
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat PHGPx
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    P9951Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat PHGPx
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    P9951Rb-r
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    Polyclonal Antibody for Rat PHGPx
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    P9951Rb-m
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    Polyclonal Antibody for Rat PHGPx
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    P9951Rb-r
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    Packing:
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    Polyclonal Antibody for Rat PHGPx
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    P9951Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat PHGPx
    Polyclonal Antibody for Rat PHGPx
    Monoclonal Antibody for Rat PHGPx
    Monoclonal Antibody for Rat PHGPx
    Monoclonal Antibody for Rat PHGPx
    Monoclonal Antibody for Rat PHGPx
    Monoclonal Antibody for Rat PHGPx
    Monoclonal Antibody for Rat PHGPx
    Monoclonal Antibody for Rat PHGPx
    Protein for Rat PHGPx
    Protein for Rat PHGPx
    Protein for Rat PHGPx
    Protein for Rat PHGPx
    Protein for Rat PHGPx
    Protein for Rat PHGPx
    Protein for Rat PHGPx

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    References
    1. 1.
      "Rat phospholipid-hydroperoxide glutathione peroxidase. cDNA cloning and identification of multiple transcription and translation start sites."
      Pushpa-Rekha T.R. , Burdsall A.L. , Oleksa L.M. , Chisolm G.M. , Driscoll D.M.
      J. Biol. Chem.270:26993-26999(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Testis.
    2. 2.
      "Distinct promoters determine alternative transcription of gpx-4 into PHGPx variants."
      Maiorino M. , Scapin M. , Ursini F. , Biasolo M. , Bosello V. , Flohe L.
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Wistar.
    3. 3.
      "Molecular cloning and functional expression of a cDNA for rat phospholipid hydroperoxide glutathione peroxidase: 3'-untranslated region of the gene is necessary for functional expression."
      Imai H. , Sumi D. , Hanamoto A. , Arai M. , Sugiyama A. , Chiba N. , Kuchino Y. , Nakagawa Y.
      J. Biochem.118:1061-1067(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-197
      strain: Sprague-Dawley.
      tissue: Brain.
    4. 4.
      "Rat liver phospholipid hydroperoxide glutathione peroxidase."
      Sunde R.A. , Dyer J.A. , Moran T.V. , Evenson J.K.
      Submitted (1993-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 21-197
      strain: Sprague-Dawley.
      tissue: Liver.
    5. 5.
      "Phospholipid hydroperoxide glutathione peroxidase of rat testis. Gonadotropin dependence and immunocytochemical identification."
      Roveri A. , Casasco A. , Maiorino M. , Dalan P. , Calligaro A. , Ursini F.
      J. Biol. Chem.267:6142-6146(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
      tissue: Testis.
    6. 6.
      "Identification of novel immunodominant epididymal sperm proteins using combinatorial approach."
      Khan S.A. , Suryawanshi A.R. , Ranpura S.A. , Jadhav S.V. , Khole V.V.
      Reproduction138:81-93(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;TISSUE SPECIFICITY
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